Preclinical Neuroimaging

Group Leader

Francisco López-Picón, PhD

Senior Researcher, PET Preclinical Imaging, Medicity Research Laboratory

francisco.lopez@utu.fi

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Aims

We work in the development and characterization of novel positron emission tomography (PET) radiotracers to investigate disease relevant targets for neurodegenerative, neuroinflammatory and neuropsychiatric diseases. We have special interest in engineering antibodies that are able to cross the blood brain barrier and use them as PET radiotracer to image brain targets (ImmunoPET approach). Furthermore, we used relevant disease models of neurodegeneration and neuroinflammation in conjunction with the PET radiotracers to investigate disease progression, and perform longitudinal pharmacological intervention studies.